منابع مشابه
Interstitial cystitis intravesical therapy
Interstitial cystitis (IC) is a progressive bladder disorder that presents with symptoms of bladder urgency, frequency and pain. The aetiology of the disease remains uncertain, but it is postulated that there is an initial infective insult which damages the glycosaminoglycan (GAG) layer of the bladder urothelium. This defect allows an influx of ions, particularly potassium, which initiates an i...
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Intratumoral gene transfer may be a significant tool in active immunotherapy. The ability to insert functional genes into a tumor in vitro and in vivo using recombinant vaccinia vectors was examined in the murine bladder tumor model. Vaccinia recombinants expressing the influenza hemagglutinin or nucleoprotein antigens infected/transfected murine (MB-49 and MBT-2) and human (T24) bladder tumor ...
متن کاملBacillus Calmette-Guerin cystitis after intravesical therapy.
Dear Editor, Since 1976 Bacillus Calmette-Guerin (an attenuated form of wild type Mycobacterium bovis; BCG) has been extensively used for the treatment of superficial bladder cancer. It is a safe and well tolerated treatment with rare adverse events including allergic reactions, granoulomatous prostitidis or epididymo-orchitis, disseminated infection and BCG sepsis1. Although cystitis is not an...
متن کاملIntravesical therapy in superficial bladder cancer.
OBJECTIVE To identify the appropriate characteristics of superficial bladder cancer that allow the physician to predict tumor behavior. METHODS We analyzed 1,745 patients with primary superficial bladder cancer with regard to disease and patient characteristics. RESULTS With the characteristics we found, the population can be described and prognostic factors can be found. Moreover, with the...
متن کاملIntravesical Therapy for Superficial Bladder Cancer
The intravesical instillation of therapeutic agents for the treatment of localized bladder cancer began in 1903 when Herring[1] summarized his experience with silver nitrate. Since then, intravesical chemotherapy and immunotherapy have emerged as effective adjuncts to endoscopic resection for superficial transitional cell carcinoma of the bladder. Although advances in the treatment of superfici...
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ژورنال
عنوان ژورنال: Urologic Clinics of North America
سال: 2020
ISSN: 0094-0143
DOI: 10.1016/j.ucl.2019.09.011